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应用生态学报 ›› 2003, Vol. ›› Issue (6): 982-984.

• 研究论文 • 上一篇    下一篇

涕灭威及其复合污染对斑马鱼胚胎DNA的影响

李阳, 张清敏, 戴树桂   

  1. 南开大学环境科学与工程学院, 天津 300071
  • 收稿日期:2002-07-05 修回日期:2003-02-28
  • 通讯作者: 李阳,女,1979年生,硕士生,主要从事环境生物学和环境毒理学研究,发表论文1篇.Tel:022-83611636,E-mail:liyang0805@sina.com.cn.
  • 基金资助:
    国家自然科学基金重点资助项目(29837170)

Impact of aldicarb and its complex pollution on DNA of zebrafish embryo

LI Yang, ZHANG Qingmin, DAI Shugui   

  1. College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China
  • Received:2002-07-05 Revised:2003-02-28

摘要: 研究了一种毒性很高的氨基甲酸酯类杀虫剂——涕灭威和广泛使用的阴离子表面活性剂十二烷基苯磺酸钠(SDBS)组成的复合污染体系对斑马鱼胚胎DNA的影响.结果表明,涕灭威对斑马鱼胚胎DNA的损伤随浓度增大而加重,但低浓度涕灭威在短时间内造成的DNA单链断裂是可以修复的,高浓度则导致难以修复的双链断裂.一定浓度(20mg·L-1)的SDBS在复合污染体系中能减弱涕灭威的毒性.

关键词: 涕灭威, 十二烷基苯磺酸钠, 斑马鱼胚胎, DNA损伤与修复

Abstract: This paper deals with the impact of a complex pollution system composed of a very toxic carbamate pesticide,aldicarb and the widely used anionic surfactant,sodium dodecylbenzenesulfonate(SDBS),on DNA of zebrafish(Brachydanio rerio) embryo. The results indicated that DNA damage caused by aldicarb became more serious with its increasing concentration,but single strand break caused by aldicarb in low concentration and short time could be repaired,and high concentration led to double strand break which was difficult to repaire. SDBSin certain concentration (20 mg稬-1) could reduce the toxicity of aldicarb in the complex pollution system.

Key words: Aldicarb, Sodium dodecylbenzenesulfonate, Zebrafish embryo, DNA damage and repair

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