Abstract: The Baiyangdian Wetland Natural Reserve is an important breeding habitat for oriental great reed warbler (OGRWs), Acrocephalus orientalis, in North China Plain. We investigated the nesting sites of OGRWs by line transect method during June-July, 2011, and 112 nests were found out in total. The ecologicalniche factor analysis (ENFA) was applied in nesting habitat suitability assessment for OGRWs in Baiyangdian. The results showed that OGRWs in this reserve preferred nesting in dry land reed landscapes, which located at relatively high altitudes and away from anthropocentric disturbance. In 2011, the suitable and the most suitable nesting habitats of OGRWs in this reserve were 2474.69 hm² and 1131.19 hm², accounting 7.6% and 3.5% of the total reserve area, respectively. The most suitable nesting habitats shaped a circle-like structure, and they all clustered together around Damai and Shaoche core area, which located in the east part of the reserve. In order to protect the nesting habitats for OGRWs within Baiyangdian wetland reserve, it was suggested that the functional zone should be reorganized, and that the Damai and Shaoche core area should be integrated into one. This new core area would be bigger and more concentrated, at the same time the buffer zone should also be established appropriately, so as to protect the natural landscapes in this reserve as much as possible.