Abstract: In recent decades, antibiotics have been widely used as the medicines for human and livestock. However, a large percentage of ingested antibiotics in living organisms are not metabolized but excreted and released as toxic contaminants, inducing their incremental residue in soil and aquatic environment, and resulting in adverse effects on living organisms and ecosystems. This paper summarized the research progress in molecular ecotoxicology of antibiotics, molecular mechanisms of antibiotics toxicity to living organisms and ecosystems, and ecotoxicological studies on molecular biomarkers of antibiotics, and summed up the new molecular diagnostic techniques applied in ecotoxicology. Some deficiencies of current molecular ecotoxicological diagnosis were pointed out, and the future study on the ecotoxicology of antibiotics was prospected.

Key words: Methyl parathion, Ferment, Supernatant, Pellet extract, Crude enzyme, Detergent