Abstract: Field trial and physiological determination on the effects of zinc and boron nutrition on balsam pear (Momordica charantia) abstract yield and quality and on polyamines, hormone, and senescence of its leaves showed that application of ZnSO₄?7H₂O and Na₂B4_O7?10H₂O on Zn and B deficient soils could increase balsam pear yield and its contents of protein, Vc and 17 sorts of amino acids, especially the contents of essential amino acids for human body, but decrease the NO₃^--N content. The reason was that Zn and B could increase polyamines (PAs) abstract, putrescine (Put) abstract, spermidine (Spd) abstract, spermine (Spm) abstract, indole acetic acid (IAA) abstract, gibberellic acid (GA₃) abstract and ascorbic acid (ASA) abstract contents and superoxide dismutase (SOD) abstract, peroxidase (POD) abstract and catalase(CAT) abstract activities, and reduce malondialdehyde (MDA) abstract, abscisic acid (ABA) abstract contents in leaves, which inhibited membrane lipid peroxidation. The results also showed that there was a significant positive correlation between yields and PAs, Put, Spd, Spm, GA₃, SOD, POD, CAT, but a significant negative correlation with MDA and ABA contents in leaves. There was a significant positive correlation between MDA and ABA, but a significant negative correlation with PAs, Put, Spd, Spm, IAA, GA₃, ASA, SOD, POD, and CAT.