Climate, vegetation and human activities have influences on regional fire regimes. To understand the fire regimes for ecological zones on national scale is the base for carrying on the forest fire management. Daily observed temperature and precipitation data in 1961-2010 were interpolated into grids for China mainland with spatial resolution of 0.25° × 0.25°, which was used to analyze their changes in fire season for eight ecological zones. Mann-Kendall test method was used for trend analysis of climate and fire dynamics. The results indicated that the average temperature for the areas with forests showed a significant linear upward trend in 1961-2010, but the precipitation didn’t have the tendency. The average temperature in fire season for all the ecological zones increased significantly in the study period, and the most increment occurred in temperate semiarid/arid steppe regions. There was no significant change in precipitation in fire season for most regions. Forest fire numbers for the mainland showed obvious fluctuations, but the affected forest areas decreased significantly. The curves of fire numbers and affected forest areas showed a bimodal shape for all ecological zones, except those showed a significant increase in the coniferous forest region in the temperate arid areas.