Abstract: By using ICP-MS method,this paper determined the accumulation of La in mice liver after the mice being fed with La(NO₃)₃ water solution for thirty days,and through in vitroexperiment,studied the effect of La(NO₃)₃ on the micronucleus rate of mice bone marrow cells and the cleavage action of La(NO₃)₃ on genome DNA to investigate the genetic toxicity of La.The results showed that when the treated concentration was 1 000,500,300 and 50 μg·ml^-1,the amount of La in mice liver reached 1.46,0.558,0.529 and 0.083 μg·g^-1,respectively.Compared with control,the La amount in disposed groups' mice livers increased with increasing La(NO₃)₃ concentration in water(r=0.980).T-test results showed that there existed significant differences in 1 000,500 and 300 μg·ml^-1 disposed groups when compared with the control(P<0.05).The micronucleus rate of mice bone marrow cells increased with increasing La(NO₃)₃ concentration in water(r=0.853).The in vitro experiments showed that La(NO₃)₃ could make DNA cleaved.It could be concluded that that La might be accumulated in organisms,and could induce the damage of genetic material in cells.

Key words: Conservation tillage, No-tillage, Soil erosion, China