Abstract: In order to supply experimental basis for developing high quality and special use wheat for Tibet,multi varieties experiments in different regions were carried out to study the quality variation of wheat varieties during1998 to 2001. Field trials of sowing in spring and in autumn were conducted in Linzhi,Rikaze,Lasa and Beijing,and 5 indices including grain protein content,wet gluten content,sedimentation value,falling number and grain hardness were determined. The results showed that the quality characters were significantly different among the varieties,and extremely significant among the sites of same variety. The protein content of grains had a positive correlation to the other 4 indices,and could be a core index in quality characters of wheat. The parameters of quality characters were higher in inland varieties than in Tibet ones,the latter appearing weak or medium gluten,and those of the same varieties were higher in Beijing than in Tibet. When inland varieties were planted in Tibet,the parameters of quality characters would be decreased. The same variety in3 sites of Tibet had different quality characters. There was a positive correlation between ecological height (latitude譭levation) and growth development duration of varieties,but a negative correlation between growth development duration and protein content,and between ecological height and protein content. Medium gluten varieties should be mainly planted in Tibet,and some good inland varieties could be introduced and planted according to the quality regionalization.