ISSN 1001-9332 CN 21-1253/Q
应用生态学报 ›› 2025, Vol. 36 ›› Issue (5): 1567-1578.doi: 10.13287/j.1001-9332.202505.033
马俊1, 李珊1, 吴亚胜2, 贺超兴3*
收稿日期:2024-11-28
修回日期:2025-03-20
出版日期:2025-05-18
发布日期:2025-11-18
通讯作者:
*E-mail: hechaoxing@caas.cn
作者简介:马 俊, 女, 1986年生, 副教授。主要从事设施园艺生理生态和植物与微生物互作研究。E-mail: lvlsmaggie@163.com
基金资助:MA Jun1, LI Shan1, WU Yasheng2, HE Chaoxing3*
Received:2024-11-28
Revised:2025-03-20
Online:2025-05-18
Published:2025-11-18
摘要： 土壤中有害重金属会抑制植物生长,严重影响作物产量和品质。植物根、茎、叶等部位的质膜和液泡膜上广泛分布着天然抗性相关巨噬细胞转运蛋白(NRAMP),其氨基酸序列在各物种间高度保守并具有类似的二级结构。这些蛋白调控着土壤重金属的吸收及其在植物体内的隔离、分配和向地上部分运输。NRAMP基因在调控植物对土壤重金属的吸收和耐受性方面起重要作用,基于近年来对NRAMP的研究,本文综述了该家族成员的结构特征以及在不同植物中对多种重金属元素的吸收、转运、积累和解毒作用,探讨了植物NRAMP基因影响土壤重金属吸收作用机理及调控途径,为进一步揭示植物NRAMP家族基因的作用机理和推动土壤环境改善提供参考。
马俊, 李珊, 吴亚胜, 贺超兴. 重金属吸收转运调控基因NRAMP的功能及其作用机理研究进展[J]. 应用生态学报, 2025, 36(5): 1567-1578.
MA Jun, LI Shan, WU Yasheng, HE Chaoxing. Advance in NRAMP gene functions in regulating plant heavy metal absorption and transport[J]. Chinese Journal of Applied Ecology, 2025, 36(5): 1567-1578.
| [1] 吴磊, 孙奇, 赵骥民, 等. 花部重金属积累对植物-传粉昆虫互惠关系影响的研究进展. 应用生态学报, 2022, 33(5): 1429-1434 [2] Khan S, Naushad M, Lima EC, et al. Global soil pollution by toxic elements: Current status and future perspectives on the risk assessment and remediation strategies: A review. Journal of Hazardous Materials, 2021, 417: 126039 [3] Xu DM, Fu RB, Liu HQ, et al. Current knowledge from heavy metal pollution in Chinese smelter contaminated soils, health risk implications and associated remediation progress in recent decades: A critical review. Journal of Cleaner Production, 2021, 286: 124989 [4] Ehrnstorfer IA, Geertsma ER, Pardon E, et al. Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport. Nature Structural & Molecular Biology, 2014, 21: 990-996 [5] Gu D, Zhou X, Ma Y, et al. Expression of a Brassica napus metal transport protein (BnMTP3) in Arabidopsis thaliana confers tolerance to Zn and Mn. Plant Science, 2021, 304: 110754 [6] Khan N, You FM, Datla R, et al. Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.). BMC Genomics, 2020, 21(1): 722 [7] Zheng J, Ma Y, Liang Y, et al. An integration of genome-wide survey, homologous comparison and gene expression analysis provides a basic framework for the ZRT, IRT-like protein (ZIP) in foxtail millet. Frontiers in Plant Science, 2024, 15: 1467015 [8] Zhang M, Chang MH, Li H, et al. MsYSL6, A metal transporter gene of alfalfa, increases iron accumulation and benefits cadmium resistance. Plants, 2023: 12 [9] Tang RJ, Luan S. Regulation of calcium and magnesium homeostasis in plants: From transporters to signaling network. Current Opinion in Plant Biology, 2017, 39: 97-105 [10] Dahuja A, Kumar RR, Sakhare A, et al. Role of ATP-binding cassette transporters in maintaining plant homeostasis under abiotic and biotic stresses. Physiologia Plantarum, 2021, 171: 785-801 [11] Liu H, Lu C, Liu XQ, et al. A chloroplast localized heavy metal-associated domain containing protein regulates grain calcium accumulation in rice. Nature Communications, 2024, 15: 9265 [12] Che J, Yamaji N, Ma JF. Role of a vacuolar iron transporter OsVIT2 in the distribution of iron to rice grains. New Phytologist, 2021, 230: 1049-1062 [13] Sooksa-Nguan T, Yakubov B, Kozlovskyy VI, et al. Drosophila ABC transporter, DmHMT-1, confers tole-rance to cadmium. Journal of Biological Chemistry, 2009, 284: 354-362 [14] Mani A, Sankaranarayanan K. Natural resistance-asso-ciated macrophage proteins (NRAMPs): Functional significance of metal transport in plants// Kumar K, Srivastava S, eds. Plant Metal and Metalloid Transpor-ters. Singapore: Springer Nature, 2022: 91-107 [15] Qin L, Han P, Chen L, et al. Genome-wide identification and expression analysis of NRAMP family genes in soybean (Glycine max L.). Frontiers in Plant Science, 2017, 8: 1436 [16] Tian W, He G, Qin L, et al. Genome-wide analysis of the NRAMP gene family in potato (Solanum tubero-sum): Identification, expression analysis and response to five heavy metals stress. Ecotoxicology and Environmental Safety, 2021, 208: 111661 [17] Li J, Duan Y, Han Z, et al. Genome-wide identification and expression analysis of the NRAMP family genes in tea plant (Camellia sinensis). Plants, 2021, 10: 1055 [18] Cellier M, Belouchi A, Gros P. Resistance to intracellular infections: Comparative genomic analysis of NRAMP. Trends in Genetics, 1996, 12: 201-204 [19] Bozzi AT, Gaudet R. Molecular mechanism of NRAMP-family transition metal transport. Journal of Molecular Biology, 2021, 433: 166991 [20] Cellier MFM, Bergevin I, Boyer E, et al. Polyphyletic origins of bacterial NRAMP transporters. Trends in Genetics, 2001, 17: 365-370 [21] Bashir K, Rasheed S, Kobayashi T, et al. Regulating subcellular metal homeostasis: The key to crop improvement. Frontiers in Plant Science, 2016, 7: 1192 [22] Chang JD, Gao W, Wang P, et al. OsNRAMP5 is a major transporter for lead uptake in rice. Environmental Science & Technology, 2022, 56: 17481-17490 [23] Castaings L, Alcon C, Kosuth T, et al. Manganese triggers phosphorylation-mediated endocytosis of the Arabidopsis metal transporter NRAMP1. The Plant Journal, 2021, 106: 1328-1337 [24] Zhao Y, Xie Q, Yang Q, et al. Genome-wide identification and evolutionary analysis of the NRAMP gene family in the AC genomes of Brassica species. BMC Plant Bio-logy, 2024, 24: 311 [25] Zhou M, Li Y, Yao XL, et al. Inorganic nitrogen inhi-bits symbiotic nitrogen fixation through blocking NRAMP2-mediated iron delivery in soybean nodules. Nature Communications, 2024, 15: 8946 [26] Guo Z, Lv J, Zhang H, et al. Red and blue light function antagonistically to regulate cadmium tolerance by modulating the photosynthesis, antioxidant defense system and Cd uptake in cucumber (Cucumis sativus L.). Journal of Hazardous Materials, 2022, 429: 128412 [27] Zhang Y, He T, Tian W, et al. The expression of the StNRAMP2 gene determined the accumulation of cad-mium in different tissues of potato. International Journal of Molecular Sciences, 2023, 24: 9322 [28] Liu J, Bao X, Qiu G, et al. Genome-wide identification and expression analysis of SlNRAMP genes in tomato under nutrient deficiency and cadmium stress during arbuscular mycorrhizal symbiosis. International Journal of Molecular Sciences, 2024, 25: 8269 [29] Zheng X, Jiang J, Wang C, et al. NRAMP6c plays a key role in plant cadmium accumulation and resistance in tobacco (Nicotiana tabacum L.). Ecotoxicology and Environmental Safety, 2024, 271: 115885 [30] Liu S, Long T, Chen Z, et al. Genome-wide identification of NRAMP family genes in Populus trichocarpa and their roles in transport of heavy metals. Tree Genetics & Genomes, 2023, 19: 51 [31] Ma Y, Huang Y, Zhang W, et al. RsNRAMP5, a major metal transporter, promotes cadmium influx and ROS accumulation in radish (Raphanus sativus L.). Plant Physiology and Biochemistry, 2025, 218: 109323 [32] Ray S, Berry SP, Wilson EA, et al. High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an NRAMP transporter. eLife, 2023, 12: e84006 [33] Ray S, Berry SP, Gaudet R. Structural basis of metal import by NRAMP family transporters. Biophysical Journal, 2023, 122: 192a [34] Adil MF, Sehar S, Chen G, et al. Cadmium-zinc cross-talk delineates toxicity tolerance in rice via differential genes expression and physiological/ultrastructural adjustments. Ecotoxicology and Environmental Safety, 2020, 190: 110076 [35] Chang J, Huang S, Yamaji N, et al. OsNRAMP1 transporter contributes to cadmium and manganese uptake in rice. Plant, Cell & Environment, 2020, 43: 2476-2491 [36] Takahashi R, Ishimaru Y, Senoura T, et al. The OsNRAMP1 iron transporter is involved in Cd accumulation in rice. Journal of Experimental Botany, 2011, 62: 4843-4850 [37] Tiwari M, Sharma D, Dwivedi S, et al. Expression in Arabidopsis and cellular localization reveal involvement of rice NRAMP, OsNRAMP1, in arsenic transport and tolerance. Plant, Cell & Environment, 2014, 37: 140-152 [38] Yang M, Zhang Y, Zhang L, et al. OsNRAMP5 contri-butes to manganese translocation and distribution in rice shoots. Journal of Experimental Botany, 2014, 65: 4849-4861 [39] Chang JD, Huang S, Konishi N, et al. Overexpression of the manganese/cadmium transporter OsNRAMP5 reduces cadmium accumulation in rice grain. Journal of Experimental Botany, 2020, 71: 5705-5715 [40] Ishimaru Y, Takahashi R, Bashir K, et al. Characterizing the role of rice NRAMP5 in manganese, iron and cadmium transport. Scientific Reports, 2012, 2: 286 [41] Yu E, Wang W, Yamaji N, et al. Duplication of a manganese/cadmium transporter gene reduces cadmium accumulation in rice grain. Nature Food, 2022, 3: 597-607 [42] Zhao J, Yang W, Zhang S, et al. Genome-wide association study and candidate gene analysis of rice cadmium accumulation in grain in a diverse rice collection. Rice, 2018, 11: 61 [43] Chang JD, Xie Y, Zhang H, et al. The vacuolar transporter OsNRAMP2 mediates Fe remobilization during germination and affects Cd distribution to rice grain. Plant and Soil, 2022, 476: 79-95 [44] Yang W, Chen L, Ma Y, et al. OsNRAMP2 facilitates Cd efflux from vacuoles and contributes to the difference in grain Cd accumulation between Japonica and Indica rice. The Crop Journal, 2023, 11: 417-426 [45] Hao X, Mo Y, Ji W, et al. The OsNramp4 aluminum transporter is involved in cadmium accumulation in rice grains. Reproduction and Breeding, 2022, 2: 125-132 [46] Yue X, Song J, Fang B, et al. BcNRAMP1 promotes the absorption of cadmium and manganese in Arabidopsis. Chemosphere, 2021, 283: 131113 [47] Li L, Zhu Z, Liao Y, et al. NRAMP6 and NRAMP1 cooperatively regulate root growth and manganese translocation under manganese deficiency in Arabidopsis. The Plant Journal, 2022, 110: 1564-1577 [48] Yu W, Deng S, Chen X, et al. PcNRAMP1 enhances cadmium uptake and accumulation in Populus ×canescens. International Journal of Molecular Sciences, 2022, 23: 7593 [49] Liu W, Huo C, He L, et al. The NtNRAMP1 transporter is involved in cadmium and iron transport in tobacco (Nicotiana tabacum). Plant Physiology and Biochemistry, 2022, 173: 59-67 [50] Jia H, Yin Z, Xuan D, et al. Mutation of NtNRAMP3 improves cadmium tolerance and its accumulation in tobacco leaves by regulating the subcellular distribution of cadmium. Journal of Hazardous Materials, 2022, 432: 128701 [51] Tejada-Jiménez M, Castro-Rodríguez R, Kryvoruchko I, et al. Medicago truncatula natural resistance-associated macrophage protein1 is required for iron uptake by rhizobia-infected nodule cells. Plant Physiology, 2015, 168: 258-272 [52] Oomen RJFJ, Wu J, Lelièvre F, et al. Functional cha-racterization of NRAMP3 and NRAMP4 from the metal hyperaccumulator Thlaspi caerulescens. New Phytologist, 2009, 181: 637-650 [53] Qian M, Li X, Tang L, et al. VrNramp5 is responsible for cadmium and manganese uptake in Vigna radiata roots. Environmental and Experimental Botany, 2022, 199: 104867 [54] Wu D, Yamaji N, Yamane M, et al. The HvNramp5 transporter mediates uptake of cadmium and manganese, but not iron. Plant Physiology, 2016, 172: 1899-1910 [55] Yu Y, Rong K, Sui X, et al. Analysis of NRAMP genes in the Triticeae reveals that TaNRAMP5 positively regulates cadmium (Cd) tolerance in wheat (Triticum aestivum). Plant Physiology and Biochemistry, 2025, 219: 109321 [56] Yokosho K, Yamaji N, Ma JF. Buckwheat FeNramp5 mediates high manganese uptake in roots. Plant and Cell Physiology, 2021, 62: 600-609 [57] Zhang L, Gao PP, Sun X, et al. BrNramp1 contributes to cadmium and manganese uptake in Brassica rapa. Plant and Soil, 2025, DOI: 10.1007/s11104-025-07236-6 [58] 邹晓燕, 王林杰, 黄杰, 等. 柱花草SgNramp1和SgNramp2基因克隆与表达分析. 草地学报, 2022, 30(6): 1388-1395 [59] Xie D, Ma X, Zhao Y, et al. Absorption, transport and regulation of manganese in plants. Scientia Sinica Vitae, 2023, 53: 1199-1212 [60] Yamaji N, Sasaki A, Xia JX, et al. A node-based switch for preferential distribution of manganese in rice. Nature Communications, 2013, 4: 2442 [61] Sasaki A, Yamaji N, Yokosho K, et al. Nramp5 is a major transporter responsible for manganese and cad-mium uptake in rice. The Plant Cell, 2012, 24: 2155-2167 [62] Ueno D, Sasaki A, Yamaji N, et al. A polarly localized transporter for efficient manganese uptake in rice. Nature Plants, 2015, 1: 1-8 [63] 裴峰, 王广达, 高鹏, 等. 敲除OsNramp5基因创制低镉优质粳稻新材料的应用评价. 中国水稻科学, 2023, 37(1): 16-28 [64] Peris-Peris C, Serra-Cardona A, Sánchez-Sanuy F, et al. Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice. Molecular Plant-Microbe Interactions, 2017, 30: 385-398 [65] Ishikawa S. Mechanisms of cadmium accumulation in rice grains and molecular breeding for its reduction. Soil Science and Plant Nutrition, 2020, 66: 28-33 [66] 董家瑜, 吴天昊, 孙远涛, 等. 不同锰浓度环境下OsNRAMP5突变对水稻耐热性和主要经济性状的影响. 杂交水稻, 2021, 36(2): 79-88 [67] Stefanache A, Lungu II, Butnariu IA, et al. Understanding how minerals contribute to optimal immune function. Journal of Immunology Research, 2023, 2023: 1-26 [68] Cailliatte R, Schikora A, Briat JF, et al. High-affinity manganese uptake by the metal transporter NRAMP1 is essential for Arabidopsis growth in low manganese conditions. The Plant Cell, 2010, 22: 904-917 [69] Castaings A, Lhomme W, Trigui R, et al. Comparison of energy management strategies of a battery/supercapa-citors system for electric vehicle under real-time constraints. Applied Energy, 2016, 163: 190-200 [70] Thomine S, Lelièvre F, Debarbieux E, et al. AtNRAMP3, a multispecific vacuolar metal transporter involved in plant responses to iron deficiency. The Plant Journal, 2003, 34: 685-695 [71] Alejandro S, Höller S, Meier B, et al. Manganese in plants: From acquisition to subcellular allocation. Frontiers in Plant Science, 2020, 11: 300 [72] Li J, Wang L, Zheng L, et al. A functional study identifying critical residues involving metal transport activity and selectivity in natural resistance-associated macrophage protein 3 in Arabidopsis thaliana. International Journal of Molecular Sciences, 2018, 19: 1430 [73] Zhang J, Zhang X, Jia M, et al. Two novel transporters NtNRAMP6a and NtNRAMP6b are involved in cadmium transport in tobacco (Nicotiana tabacum L.). Plant Physiology and Biochemistry, 2023, 202: 107953 [74] Ullah I, Wang Y, Eide DJ, et al. Evolution, and functional analysis of natural resistance-associated macrophage proteins (NRAMPs) from Theobroma cacao and their role in cadmium accumulation. Scientific Reports, 2018, 8: 14412 [75] Meng JG, Zhang XD, Tan SK, et al. Genome-wide identification of Cd-responsive NRAMP transporter genes and analyzing expression of NRAMP1 mediated by miR167 in Brassica napus. Biometals, 2017, 30: 917-931 [76] Zou X, Huang R, Wang L, et al. SgNramp1, a plasma membrane-localized transporter, involves in manganese uptake in Stylosanthes guianensis. Frontiers in Plant Science, 2022, 13: 1027551 [77] Yang CH, Zhang Y, Huang CF. Reduction in cadmium accumulation in Japonica rice grains by CRISPR/Cas9-mediated editing of OsNRAMP5. Journal of Integrative Agriculture, 2019, 18: 688-697 [78] Huang G, Ding X, Liu Y, et al. Liming and tillering application of manganese alleviates iron manganese plaque reduction and cadmium accumulation in rice (Oryza sativa L.). Journal of Hazardous Materials, 2022, 427: 127897 [79] Wang Y, Xu Y, Liang X, et al. Soil application of manganese sulfate could reduce wheat Cd accumulation in Cd contaminated soil by the modulation of the key tissues and ionomic of wheat. Science of the Total Environment, 2021, 770: 145328 [80] Ma W, Li Y, Ge C, et al. Effect of genotype on cad-mium and trace element accumulation in wheat from weakly alkaline cadmium-contaminated soil. Bulletin of Environmental Contamination and Toxicology, 2024, 113: 9 [81] 李小秀, 吕启明, 袁定阳. OsNramp5基因变异影响水稻重要农艺性状的研究进展. 中国水稻科学, 2022, 36(6): 562-571 [82] Kanwal F, Riaz A, Ali S, et al. NRAMPs and manganese: Magic keys to reduce cadmium toxicity and accumulation in plants. Science of the Total Environment, 2024, 921: 171005 [83] Bereczky Z, Wang HY, Schubert V, et al. Differential regulation of NRAMP and IRT metal transporter genes in wild type and iron uptake mutants of tomato. Journal of Biological Chemistry, 2003, 278: 24697-24704 [84] Thomine S, Wang R, Ward JM, et al. Cadmium and iron transport by members of a plant metal transporter family in Arabidopsis with homology to Nramp genes. Proceedings of the National Academy of Sciences of the United States of Ameria, 2000, 97: 4991-4996 [85] Li Y, Li J, Yu Y, et al. The tonoplast-localized transporter OsNRAMP2 is involved in iron homeostasis and affects seed germination in rice. Journal of Experimental Botany, 2021, 72: 4839-4852 [86] Pottier M, Oomen R, Picco C, et al. Identification of mutations allowing natural resistance associated macrophage proteins (NRAMP) to discriminate against cadmium. The Plant Journal, 2015, 83: 625-637 [87] Hussain Q, Ye T, Shang C, et al. NRAMP gene family in Kandelia obovata: Genome-wide identification, expression analysis, and response to five different copper stress conditions. Frontiers in Plant Science, 2024, 14: 1318383 [88] Peng F, Wang C, Zhu J, et al. Expression of TpNRAMP5, a metal transporter from Polish wheat (Triticum polonicum L.), enhances the accumulation of Cd, Co and Mn in transgenic Arabidopsis plants. Planta, 2018, 247: 1395-1406 [89] 李嘉欣, 李鸿燕, 刘丽娥, 等. 沙棘NRAMP基因家族鉴定及铅胁迫下表达分析. 生物技术通报, 2024, 40(5): 191-202 [90] Liu H, Zhang C, Wang J, et al. Influence and interaction of iron and cadmium on photosynthesis and antioxidative enzymes in two rice cultivars. Chemosphere, 2017, 171: 240-247 [91] Liu HJ, Zhang JL, Zhang FS. Role of iron plaque in Cd uptake by and translocation within rice (Oryza sativa L.) seedlings grown in solution culture. Environmental and Experimental Botany, 2007, 59: 314-320 [92] Sebastian A, Prasad M. Iron- and manganese-assisted cadmium tolerance in Oryza sativa L.: Lowering of rhizotoxicity next to functional photosynthesis. Planta, 2015, 241: 1519-1528 [93] Liu C, Zhao Y, Wen L, et al. Integrated physiological, transcriptome-wide m6A methylation and proteome analysis reveals molecular mechanisms of tomato root response to cadmium stress. Horticultural Plant Journal, 2024, 2024: S2468014124001961 [94] Song Y, Hudek L, Freestone D, et al. Comparative analyses of cadmium and zinc uptake correlated with changes in natural resistance-associated macrophage protein (NRAMP) expression in Solanum nigrum L. and Bra-ssica rapa. Environmental Chemistry, 2014, 11: 653 [95] Zhou X, Yang Y. Differential expression of rice NRAMP genes in response to pathogen infection, defense signal molecules and metal ions. Physiological and Molecular Plant Pathology, 2004, 65: 235-243 [96] Meena M, Aamir M, Kumar V, et al. Evaluation of morpho-physiological growth parameters of tomato in response to Cd induced toxicity and characterization of metal sensitive NRAMP3 transporter protein. Environmental and Experimental Botany, 2018, 148: 144-167 [97] 余沁, 何林燊, 霍春松, 等. 烟草NRAMP家族全基因组鉴定及响应重金属胁迫的表达分析. 分子植物育种, 2022, 20(5): 1496-1504 [98] 李亚敏, 巩宗强, 贾春云, 等. 玉米镉转运基因ZmNramp1的鉴定及对镉胁迫的响应. 生态学杂志, 2021, 40(7): 2016-2023 [99] Zhiguo E, Tingting L, Chen C, et al. Genome-wide survey and expression analysis of P1B -ATPases in rice, maize and sorghum. Rice Science, 2018, 25: 208-217 [100] Colangelo EP, Guerinot ML. Put the metal to the petal: Metal uptake and transport throughout plants. Current Opinion in Plant Biology, 2006, 9: 322-330 [101] Jabado N, Jankowski A, Dougaparsad S, et al. Natural resistance to intracellular infections: Natural resis-tance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane. The Journal of Experimental Medicine, 2000, 192: 1237-1248 [102] Bozzi AT, Zimanyi CM, Nicoludis JM, et al. Structures in multiple conformations reveal distinct transition metal and proton pathways in an NRAMP transporter. eLife, 2019, 8: e41124 [103] Chen Y, Zhao X, Li G, et al. Genome-wide identification of the NRAMP gene family in Spirodela polyrhiza and expression analysis under cadmium stress. International Journal of Molecular Sciences, 2021, 22: 6414 [104] Ma X, Yang H, Bu Y, et al. Genome-wide identification of the NRAMP gene family in Populus trichocarpa and their function as heavy metal transporters. Ecotoxicology and Environmental Safety, 2023, 261: 115110 [105] Yan L, Jin H, Raza A, et al. Natural resistance-associated macrophage proteins (NRAMPs) are involved in cadmium enrichment in peanut (Arachis hypogaea L.) under cadmium stress. Plant Growth Regulation, 2024, 102: 619-632 [106] Alonso JM, Hirayama T, Roman G, et al. EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. Science, 1999, 284: 2148-2152 [107] Chakrabarti M, Bharti S. Role of EIN2-mediated ethy-lene signaling in regulating petal senescence, abscission, reproductive development, and hormonal crosstalk in tobacco. Plant Science, 2023, 332: 111699 [108] Ma B, Zhou Y, Chen H, et al. Membrane protein MHZ3 stabilizes OsEIN2 in rice by interacting with its Nramp-like domain. Proceedings of the National Aca-demy of Sciences of the United States of America, 2018, 115: 2520-2525 [109] Mathur P, Tripathi DK, Baluška F, et al. Auxin-mediated molecular mechanisms of heavy metal and metalloid stress regulation in plants. Environmental and Experimental Botany, 2022, 196: 104796 [110] Li S, Wang HY, Zhang Y, et al. Auxin is involved in cadmium accumulation in rice through controlling nitric oxide production and the ability of cell walls to bind cadmium. Science of the Total Environment, 2023, 904: 166644 [111] 王逸筠, 胡美美, 崔秀敏, 等. 铜、镉胁迫下外源NO介导的番茄解毒途径. 应用生态学报, 2018, 29(12): 4199-4207 [112] Pan W, You Y, Shentu JL, et al. Abscisic acid (ABA)-importing transporter 1 (AIT1) contributes to the inhibition of Cd accumulation via exogenous ABA application in Arabidopsis. Journal of Hazardous Mate-rials, 2020, 391: 122189 [113] Bozzi AT, Bane LB, Weihofen WA, et al. Conserved methionine dictates substrate preference in Nramp-family divalent metal transporters. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113: 10310-10315 [114] Zhao FJ, Chang JD. A weak allele of OsNRAMP5 for safer rice. Journal of Experimental Botany, 2022, 73: 6009-6012 [115] Strader L, Weijers D, Wagner D. Plant transcription factors-being in the right place with the right company. Current Opinion in Plant Biology, 2022, 65: 102136 [116] Zhang H, Sun B, Wu W, et al. The MYB transcription factor OsMYBxoc1 regulates resistance to Xoc by directly repressing transcription of the iron transport gene OsNRAMP5 in rice. Plant Communications, 2024, 5: 100859 [117] Sun L, Wei YQ, Wu KH, et al. Restriction of iron loading into developing seeds by a YABBY transcription factor safeguards successful reproduction in Arabidopsis. Molecular Plant, 2021, 14: 1624-1639 [118] Shen C, Huang B, Hu L, et al. Comparative transcriptome analysis and Arabidopsis thaliana overexpression reveal key genes associated with cadmium transport and distribution in root of two Capsicum annuum cultivars. Journal of Hazardous Materials, 2024, 465: 133365 [119] Li J, Wang Y, Zheng L, et al. The intracellular transporter AtNRAMP6 is involved in Fe homeostasis in Arabidopsis. Frontiers in Plant Science, 2019, 10, DOI: 10.3389/fpls.2019.01124 |
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